![]() PathologyĪlthough the etiology of sarcoidosis is unknown, speculation has centered on the interaction of an unknown antigenic factor triggering an exaggerated cellular immune response in genetically susceptible individuals 1. ![]() pancreatic, intestinal, and testicular sarcoidosis have been found in 5% or less of patients at autopsy 1Ībdominal viscera are frequently involved in sarcoidosis, although this involvement usually does not produce symptoms. Symptomatic liver disease occurs in less than 5% of patients with sarcoidosis. Laboratory evidence of liver dysfunction is seen in 2-60% of patients, with the alkaline phosphatase level being most commonly affected 1.renal involvement is seen in 8-19% of patients.liver and spleen are the most frequently involved viscera, with granulomata noted in 40-70% of patients 1,2.presentation may vary widely with geography and ethnicity.The lateral aortic lymph nodes, typically 15 to 20 on each side, are the ones usually chosen for dissection or biopsy in the treatment or diagnosis of cancer.Ī dissection usually includes the region from the bifurcation of the aorta to the superior mesenteric artery or the renal veins. Most of the efferent vessels from the paraaortic nodes converge to form the right and left lumbar trunks which join the cisterna chyli, but some enter the preaortic and retroaortic lymph nodes, and others pierce the crura of the diaphragm to join the lower end of the thoracic duct. (d) the lymphatics draining the lateral abdominal muscles and accompanying the lumbar veins.(c) the lymphatics from the kidney and suprarenal gland.(b) the lymphatics from the testis in the male, and from the ovary, uterine tube, and uterus in the female.(a) the efferents of the common iliac lymph nodes.The paraaortic and retroaortic nodes receive: The left paraaortic nodes form a chain on the left side of the abdominal aorta in front of the origin of the psoas major and on the left crus of the diaphragm. The right paraaortic nodes, are situated partly in front of the inferior vena cava near the termination of the renal vein, and partly behind it on the origin of the psoas major, and on the right crus of diaphragm. The retroaortic group are sometimes included in the paraaortic group due to their position (which is also lateral) and the same pattern of lymphatic drainage.The lateral group nodes are located adjacent to the aorta, anterior to the spine, extending laterally to the edge of the psoas major muscles, and superiorly to the crura of the diaphragm. The paraaortic group (also known as lateral aortic group) drains the iliac nodes, the ovaries, the testes and other pelvic organs.They can be subdivided into three groups: the celiac nodes, the superior mesenteric nodes, and the inferior mesenteric nodes. The preaortic group drains the gastrointestinal viscera.The periaortic lymph node group is divided into three subgroups: preaortic, paraaortic, and retroaortic: The paraaortic group is synonymous with the lateral aortic group. ![]() The periaortic group is the general group, that is subdivided into: preaortic, paraaortic, and retroaortic groups. The periaortic lymph nodes are different from the paraaortic lymph nodes. ![]() These lymph nodes receive drainage from the gastrointestinal tract and the abdominal organs. The periaortic lymph nodes (also known as lumbar) are a group of lymph nodes that lie in front of the lumbar vertebrae near the aorta. ![]()
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